76 citations · 117 across the 18 of their papers we have counts for
3 papers · 1 filter
DDoS: A Graph Neural Network based Drug Synergy Prediction Algorithm
Kyriakos Schwarz, Alicia Pliego-Mendieta, Amina Mollaysa +4
Drug synergy arises when the combined impact of two drugs exceeds the sum of their individual effects. While single-drug effects on cell lines are well-documented, the scarcity of…
Drug prescription clusters in the UK Biobank: An assessment of drug-drug interactions and patient outcomes in a large patient cohort
Kyriakos Schwarz, Daniel Trejo Banos, Giulia Rathmes +1
In recent decades, there has been an increase in polypharmacy, the concurrent administration of multiple drugs per patient. Studies have shown that polypharmacy is linked to advers…
AttentionDDI: Siamese Attention-based Deep Learning method for drug-drug interaction predictions
Kyriakos Schwarz, Ahmed Allam, Nicolas Andres Perez Gonzalez +1
Background: Drug-drug interactions (DDIs) refer to processes triggered by the administration of two or more drugs leading to side effects beyond those observed when drugs are admin…