310 citations · 1.4k across the 13 of their papers we have counts for
16 papers
Deterministic access to global viral sequence data enables robust agentic scientific discovery
Ferdous Nasri, Sarah Gurev, Patrick Varilly +6
Public viral genome resources such as the National Center for Biotechnology Information (NCBI) Virus database are central to outbreak response, evolutionary analysis, vaccine desig…
Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers
Patrick Varilly, Adam P. Willard, Julius B. Kirkegaard +2
Aggregation of amphiphiles through the action of hydrophobic interactions is a common feature in soft condensed matter systems and is of particular importance in the context of bio…
Consistent treatment of hydrophobicity in protein lattice models accounts for cold denaturation
Erik van Dijk, Patrick Varilly, Tuomas Knowles +2
The hydrophobic effect stabilizes the native structure of proteins by minimizing the unfavourable interactions between hydrophobic residues and water through the formation of a hyd…
Mobile linkers on DNA-coated colloids: valency without patches
Stefano Angioletti-Uberti, Patrick Varilly, Bortolo M. Mognetti +1
Colloids coated with single-stranded DNA (ssDNA) can bind selectively to other colloids coated with complementary ssDNA. The fact that DNA-coated colloids (DNACCs) can bind to spec…
Designing stimulus-sensitive colloidal walkers
Francisco J. Martinez-Veracoechea, Bortolo M. Mognetti, Stefano Angioletti-Uberti +3
Colloidal particles with DNA `legs' that can bind reversibly to receptors on a surface can be made to `walk' if there is a gradient in receptor concentration. We use a combination…
A simple analytical formula for the free-energy of ligand-receptor mediated interactions
Stefano Angioletti-Uberti, Patrick Varilly, Bortolo Matteo Mognetti +2
Recently \1, we presented a general theory for calculat- ing the strength and properties of colloidal interactions mediated by ligand-receptor bonds (such as those that bind DNA-co…