1 citations · 1 across the 11 of their papers we have counts for
4 papers · 1 filter
Fluctuations in network dynamics: SMAR1 can trigger apoptosis
Md. Zubbair Malik, Md. Jahoor Alam, Romana Ishrat +2
SMAR1 is a sensitive signaling molecule in p53 regulatory network which can drive p53 network dynamics to three distinct states, namely, stabilized (two), damped and sustain oscill…
Dynamical patterns of p53 states driven by PML
Md. Jahoor Alam, Eyad M. AlShammari, R. K. Brojen Singh
Recent studies suggest that PML (Promyelocytic Leukemia) suppresses p53 protein degradation by inhibiting MDM2 protein in the nucleus [1], and regulates a number of biological func…
Phase transition in p53 states induced by glucose
Md. Jahoor Alam, R. K. Brojen Singh
We present p53-MDM2-Glucose model to study spatio-temporal properties of the system induced by glucose. The variation in glucose concentration level triggers the system at differen…
Dynamics of p53 and Wnt cross talk
Md. Zubbair Malik, Shahnawaz Ali, Md. Jahoor Alam +2
We present the mechanism of interaction of Wnt network module, which is responsible for periodic sometogenesis, with p53 regulatory network, which is one of the main regulators of…