3 papers
cond-mat.soft2026
A Soft Penetrable Sphere Colloid Model for the Description of Charge and Excluded Volume Interactions in Antibody Solutions
Peter Schurtenberger, Marco Polimeni, Sophia Marzouk +3
Colloid models have frequently been used to successfully describe the influence of protein-protein interactions on antibody solution properties, but they suffer from inherent probl…
cond-mat.soft2026
Beyond uniform screening: electrostatic heterogeneity dictates solution structure of complex macromolecules
Fabrizio Camerin, Marco Polimeni, Letizia Tavagnacco +7
The complexity of biomolecular interactions necessitates advanced methodologies to accurately capture their behavior in solution. In this work, we focus on monoclonal antibodies an…
cond-mat.soft2025
Electrostatics and viscosity are strongly linked in concentrated antibody solutions
Fabrizio Camerin, Marco Polimeni, Anna Stradner +2
Monoclonal antibodies are among the most promising therapeutic agents in modern medicine, yet their formulation into high-concentration solutions for subcutaneous self-administrati…