112 citations · 280 across the 9 of their papers we have counts for
3 papers · 1 filter
Predicting Cellular Responses with Variational Causal Inference and Refined Relational Information
Yulun Wu, Robert A. Barton, Zichen Wang +5
Predicting the responses of a cell under perturbations may bring important benefits to drug discovery and personalized therapeutics. In this work, we propose a novel graph variatio…
Model-free Sign Estimation for High-Throughput Screenings
Jackson Loper, Jeffrey Regier
In high-throughput screenings, it is common to estimate the effects of many treatments using a small number of independent trials of each. Because little is known about the distrib…
Neural Design for Genetic Perturbation Experiments
Aldo Pacchiano, Drausin Wulsin, Robert A. Barton +1
The problem of how to genetically modify cells in order to maximize a certain cellular phenotype has taken center stage in drug development over the last few years (with, for examp…