2 papers
physics.bio-ph2011
Electromediated formation of DNA complexes with cell membranes and its consequences for gene delivery
Jean-Michel Escoffre, Thomas Portet, Cyril Favard +3
Electroporation is a physical method to induce the uptake of therapeutic drugs and DNA, by eukaryotic cells and tissues. The phenomena behind electro-mediated membrane permeabiliza…
physics.bio-ph2011
Insights into the mechanisms of electromediated gene delivery and application to the loading of giant vesicles with negatively charged macromolecules
Thomas Portet, Cyril Favard, Justin Teissié +2
We present experimental results regarding the electrotransfer of plasmid DNA into phosphatidylcholine giant unilamellar vesicles (GUVs). Our observations indicate that a direct ent…