38 citations · 111 across the 14 of their papers we have counts for
3 papers · 1 filter
Prediction and replication from case-control sequencing studies using custom genotyping and additional sequencing
C. Ryan King, Paul J. Rathouz, Dan L. Nicolae
We present two results about using allele-count (AC) burdens of rare SNPs discovered in a case-control sequencing study for prediction or validation in an external prospective stud…
The Convergence of eQTL Mapping, Heritability Estimation and Polygenic Modeling: Emerging Spectrum of Risk Variation in Bipolar Disorder
Eric R. Gamazon, Hae Kyung Im, Chunyu Liu +4
It is widely held that a substantial genetic component underlies Bipolar Disorder (BD) and other neuropsychiatric disease traits. Recent efforts have been aimed at understanding th…
On Quantifying Dependence: A Framework for Developing Interpretable Measures
Matthew Reimherr, Dan L. Nicolae
We present a framework for selecting and developing measures of dependence when the goal is the quantification of a relationship between two variables, not simply the establishment…