302 citations · 2.5k across the 74 of their papers we have counts for
9 papers · 1 filter
Large-Scale Survey of Cell-Differentiation Programs in a Generative Model Reveals Regeneration as an Epiphenomenon of Development
Somya Mani, Tsvi Tlusty
Development combines three basic processes asymmetric --- cell division, signaling and gene regulation --- in a multitude of ways to create an overwhelming diversity of multicellul…
Efficiency fluctuations and noise induced refrigerator-to-heater transition in information engines
Govind Paneru, Sandipan Dutta, Takahiro Sagawa +2
Understanding noisy information engines is a fundamental problem of non-equilibrium physics, particularly in biomolecular systems agitated by thermal and active fluctuations in the…
Reaching and violating thermodynamic uncertainty bounds in information engines
Govind Paneru, Sandipan Dutta, Tsvi Tlusty +1
Thermodynamic uncertainty relations (TURs) set fundamental bounds on the fluctuation and dissipation of stochastic systems. Here, we examine these bounds, in experiment and theory,…
Kinetic Proofreading and the Limits of Thermodynamic Uncertainty
William D. Piñeros, Tsvi Tlusty
To mitigate errors induced by the cell's heterogeneous noisy environment, its main information channels and production networks utilize the kinetic proofreading (KPR) mechanism. He…
DCA method identifies unspecific binding but specific disruption of the group I intron by the StpA chaperone
Vladimir Reinharz, Tsvi Tlusty
Chaperone protein - the most disordered among all protein groups - help RNAs fold into their functional structure by destabilizing misfolded configurations or stabilizing the funct…
Enhanced diffusion and enzyme dissociation
Ah-Young Jee, Kuo Chen, Tsvi Tlusty +2
The concept that catalytic enzymes can act as molecular machines transducing chemical activity into motion has conceptual and experimental support, but much of the claimed support…