85 citations · 143 across the 4 of their papers we have counts for
4 papers
A Unified Statistical Framework for Single Cell and Bulk RNA Sequencing Data
Lingxue Zhu, Jing Lei, Bernie Devlin +1
Recent advances in technology have enabled the measurement of RNA levels for individual cells. Compared to traditional tissue-level bulk RNA-seq data, single cell sequencing yields…
Testing High Dimensional Covariance Matrices, with Application to Detecting Schizophrenia Risk Genes
Lingxue Zhu, Jing Lei, Bernie Devlin +1
Scientists routinely compare gene expression levels in cases versus controls in part to determine genes associated with a disease. Similarly, detecting case-control differences in…
Refining genetically inferred relationships using treelet covariance smoothing
Andrew Crossett, Ann B. Lee, Lambertus Klei +2
Recent technological advances coupled with large sample sets have uncovered many factors underlying the genetic basis of traits and the predisposition to complex disease, but much…
GemTools: A fast and efficient approach to estimating genetic ancestry
Lambertus Klei, Brian P. Kent, Nadine Melhem +2
To uncover the genetic basis of complex disease, individuals are often measured at a large number of genetic variants (usually SNPs) across the genome. GemTools provides computatio…