98 citations · 103 across the 4 of their papers we have counts for
4 papers
A mutate-and-map protocol for inferring base pairs in structured RNA
Pablo Cordero, Wipapat Kladwang, Christopher C. VanLang +1
Chemical mapping is a widespread technique for structural analysis of nucleic acids in which a molecule's reactivity to different probes is quantified at single-nucleotide resoluti…
Quantitative DMS mapping for automated RNA secondary structure inference
Pablo Cordero, Wipapat Kladwang, Christopher C. VanLang +1
For decades, dimethyl sulfate (DMS) mapping has informed manual modeling of RNA structure in vitro and in vivo. Here, we incorporate DMS data into automated secondary structure inf…
Two-dimensional chemical mapping for non-coding RNAs
Wipapat Kladwang, Christopher C. VanLang, Pablo Cordero +1
Non-coding RNA molecules fold into precise base pairing patterns to carry out critical roles in genetic regulation and protein synthesis. We show here that coupling systematic muta…
Understanding the errors of SHAPE-directed RNA structure modeling
Wipapat Kladwang, Christopher C. VanLang, Pablo Cordero +1
Single-nucleotide-resolution chemical mapping for structured RNA is being rapidly advanced by new chemistries, faster readouts, and coupling to computational algorithms. Recent tes…