5 papers
A Multimodal Clinically Informed Coarse-to-Fine Framework for Longitudinal CT Registration in Proton Therapy
Caiwen Jiang, Yuzhen Ding, Mi Jia +14
Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans…
RadOnc-GPT: An Autonomous LLM Agent for Real-Time Patient Outcomes Labeling at Scale
Jason Holmes, Yuexing Hao, Mariana Borras-Osorio +22
Manual labeling limits the scale, accuracy, and timeliness of patient outcomes research in radiation oncology. We present RadOnc-GPT, an autonomous large language model (LLM)-based…
An Automated Retrieval-Augmented Generation LLaMA-4 109B-based System for Evaluating Radiotherapy Treatment Plans
Junjie Cui, Peilong Wang, Jason Holmes +15
Purpose: To develop a retrieval-augmented generation (RAG) system powered by LLaMA-4 109B for automated, protocol-aware, and interpretable evaluation of radiotherapy treatment plan…
Causal Machine Learning Analysis of Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis in Head and Neck Cancer Radiotherapy
Jingyuan Chen, Zhong Liu, Yunze Yang +8
Mandible Osteoradionecrosis (ORN) is one of the most severe adverse events (AEs) for head and neck (H&N) cancer radiotherapy. Previous retrospective investigations on real-world da…
Evaluating The Performance of Using Large Language Models to Automate Summarization of CT Simulation Orders in Radiation Oncology
Meiyun Cao, Shaw Hu, Jason Sharp +10
Purpose: This study aims to use a large language model (LLM) to automate the generation of summaries from the CT simulation orders and evaluate its performance. Materials and Metho…