5 papers
A Multimodal Clinically Informed Coarse-to-Fine Framework for Longitudinal CT Registration in Proton Therapy
Caiwen Jiang, Yuzhen Ding, Mi Jia +14
Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans…
A 3D SAM-Based Progressive Prompting Framework for Multi-Task Segmentation of Radiotherapy-induced Normal Tissue Injuries in Limited-Data Settings
Caiwen Jiang, Lei Zeng, Wei Liu
Radiotherapy-induced normal tissue injury is a clinically important complication, and accurate segmentation of injury regions from medical images could facilitate disease assessmen…
Causal machine learning reveals age-dependent radiation dose effects on mandibular osteoradionecrosis
Jingyuan Chen, Yunze Yang, Olivia M. Muller +8
Distinguishing causal relationships from statistical correlations remains a fundamental challenge in clinical research, limiting the translation of observational findings into inte…
Dose-LET Interactions Predict Capsular Contracture After Proton Postmastectomy Radiation Therapy
Jingyuan Chen, Zeliang Ma, Meiyun Cao +9
Pencil beam scanning (PBS) proton therapy provides highly conformal dose distributions that are increasingly leveraged for postmastectomy radiation therapy (PMRT) to reduce cardiop…
Critical review of patient outcome study in head and neck cancer radiotherapy
Jingyuan Chen, Yunze Yang, Chenbin Liu +8
Rapid technological advances in radiation therapy have significantly improved dose delivery and tumor control for head and neck cancers. However, treatment-related toxicities cause…