105 citations · 275 across the 11 of their papers we have counts for
5 papers · 1 filter
Automated RNA structure prediction uncovers a missing link in double glycine riboswitches
Wipapat Kladwang, Fang-Chieh Chou, Rhiju Das
The tertiary structures of functional RNA molecules remain difficult to decipher. A new generation of automated RNA structure prediction methods may help address these challenges b…
HiTRACE: High-throughput robust analysis for capillary electrophoresis
Sungroh Yoon, Jinkyu Kim, Justine Hum +4
Motivation: Capillary electrophoresis (CE) of nucleic acids is a workhorse technology underlying high-throughput genome analysis and large-scale chemical mapping for nucleic acid s…
Can biopolymer structures be sampled enumeratively? Atomic-accuracy RNA loop modeling by a stepwise ansatz
Parin Sripakdeevong, Wipapat Kladwang, Rhiju Das
Atomic-accuracy structure prediction of macromolecules is a long-sought goal of computational biophysics. Accurate modeling should be achievable by optimizing a physically realisti…
Two-dimensional chemical mapping for non-coding RNAs
Wipapat Kladwang, Christopher C. VanLang, Pablo Cordero +1
Non-coding RNA molecules fold into precise base pairing patterns to carry out critical roles in genetic regulation and protein synthesis. We show here that coupling systematic muta…
Understanding the errors of SHAPE-directed RNA structure modeling
Wipapat Kladwang, Christopher C. VanLang, Pablo Cordero +1
Single-nucleotide-resolution chemical mapping for structured RNA is being rapidly advanced by new chemistries, faster readouts, and coupling to computational algorithms. Recent tes…