2 papers
q-bio.MN2011
Nonlinear regulation of commitment to apoptosis by simultaneous inhibition of Bcl-2 and XIAP in leukemia and lymphoma cells
Joanna Skommer, Somkanya C Das, Arjun Nair +2
Apoptosis is a complex pathway regulated by the concerted action of multiple pro- and anti-apoptotic molecules. The intrinsic (mitochondrial) pathway of apoptosis is governed up-st…
q-bio.CB2011
Timing is everything: on the stochastic origins of cell-to-cell variability in cancer cell death decisions
Joanna Skommer, Subhadip Raychaudhuri, Donald Wlodkowic
The diversity of cell populations is regulated by extracellular and intracellular variability. The latter includes genetic, epigenetic and stochastic variability, all contributing…