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physics.bio-ph2022
Computational model for tumor response to adoptive cell transfer therapy
Luciana Melina Luque, Carlos Manuel Carlevaro, Enrique Rodríguez-Lomba +1
One of the barriers to the development of effective adoptive cell transfer therapies (ACT), specifically for genetically engineered T-cell receptors (TCRs), and chimeric antigen re…
physics.bio-ph2022
Physics-based tissue simulator to model multicellular systems: A study of liver regeneration and hepatocellular carcinoma recurrence
Luciana Melina Luque, Carlos Manuel Carlevaro, Camilo Llamoza Torres +1
We present a multiagent-based model that captures the interactions between different types of cells with their microenvironment, and enables the analysis of the emergent global beh…