196 citations · 221 across the 5 of their papers we have counts for
5 papers
BIISQ: Bayesian nonparametric discovery of Isoforms and Individual Specific Quantification
Derek Aguiar, Li-Fang Cheng, Bianca Dumitrascu +3
Most human protein-coding genes can be transcribed into multiple possible distinct mRNA isoforms. These alternative splicing patterns encourage molecular diversity and dysregulatio…
TIGRESS: Trustful Inference of Gene REgulation using Stability Selection
Anne-Claire Haury, Fantine Mordelet, Paola Vera-Licona +1
Inferring the structure of gene regulatory networks (GRN) from gene expression data has many applications, from the elucidation of complex biological processes to the identificatio…
ProDiGe: PRioritization Of Disease Genes with multitask machine learning from positive and unlabeled examples
Fantine Mordelet, Jean-Philippe Vert
Elucidating the genetic basis of human diseases is a central goal of genetics and molecular biology. While traditional linkage analysis and modern high-throughput techniques often…
A bagging SVM to learn from positive and unlabeled examples
Fantine Mordelet, Jean-Philippe Vert
We consider the problem of learning a binary classifier from a training set of positive and unlabeled examples, both in the inductive and in the transductive setting. This problem,…
SIRENE: Supervised Inference of Regulatory Networks
Fantine Mordelet, Jean-Philippe Vert
Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in t…