44 citations · 226 across the 17 of their papers we have counts for
5 papers · 1 filter
Thermodynamic competition between membrane protein oligomeric states
Osman Kahraman, Christoph A. Haselwandter
Self-assembly of protein monomers into distinct membrane protein oligomers provides a general mechanism for diversity in the molecular architectures, and resulting biological funct…
Bilayer-thickness-mediated interactions between integral membrane proteins
Osman Kahraman, Peter D. Koch, William S. Klug +1
Hydrophobic thickness mismatch between integral membrane proteins and the surrounding lipid bilayer can produce lipid bilayer thickness deformations. Experiment and theory have sho…
Architecture and Function of Mechanosensitive Membrane Protein Lattices
Osman Kahraman, Peter D. Koch, William S. Klug +1
Experiments have revealed that membrane proteins can form two-dimensional clusters with regular translational and orientational protein arrangements, which may allow cells to modul…
Signatures of protein structure in the cooperative gating of mechanosensitive ion channels
Osman Kahraman, William S. Klug, Christoph A. Haselwandter
Membrane proteins deform the surrounding lipid bilayer, which can lead to membrane-mediated interactions between neighboring proteins. Using the mechanosensitive channel of large c…
Directional interactions and cooperativity between mechanosensitive membrane proteins
Christoph A. Haselwandter, Rob Phillips
While modern structural biology has provided us with a rich and diverse picture of membrane proteins, the biological function of membrane proteins is often influenced by the mechan…