activity
20112022
most citedA parameter-free model discrimination criterion based on steady-state coplanarity

34 citations · 34 across the 5 of their papers we have counts for

collaborators

5 papers

stat.CO2022

Rare event ABC-SMC

Ivis Kerama, Thomas Thorne, Richard G. Everitt

Approximate Bayesian computation (ABC) is a well-established family of Monte Carlo methods for performing approximate Bayesian inference in the case where an ``implicit'' model is…

q-bio.QM2021

Topological Approximate Bayesian Computation for Parameter Inference of an Angiogenesis Model

Thomas Thorne, Paul D. W. Kirk, Heather A. Harrington

Inferring the parameters of models describing biological systems is an important problem in the reverse engineering of the mechanisms underlying these systems. Much work has focuse…

q-bio.MN2012

Inference of Temporally Varying Bayesian Networks

Thomas Thorne, Michael P. H Stumpf

When analysing gene expression time series data an often overlooked but crucial aspect of the model is that the regulatory network structure may change over time. Whilst some appro…

q-bio.QM2011★ 34 cited

A parameter-free model discrimination criterion based on steady-state coplanarity

Heather A. Harrington, Kenneth L. Ho, Thomas Thorne +1

We describe a novel procedure for deciding when a mass-action model is incompatible with observed steady-state data that does not require any parameter estimation. Thus, we avoid t…

stat.CO2011

Considerate Approaches to Achieving Sufficiency for ABC model selection

Chris Barnes, Sarah Filippi, Michael P. H. Stumpf +1

For nearly any challenging scientific problem evaluation of the likelihood is problematic if not impossible. Approximate Bayesian computation (ABC) allows us to employ the whole Ba…