11 papers
Effect of sub-critical fluid shear flow on granular bed strength
Dong Wang, Sophie Bodek, Nicholas T. Ouellette +2
Interactions between fluids and granular materials are prevalent on the Earth's surface. In the case of fluid flow over a sediment bed, the fluid imparts a shear stress to the gran…
Preserving elastic anisotropy with tessellations of granular packings
Annie Z. Xia, Dong Wang, Catherine La Riviere +3
Multiscale periodic metamaterials have been designed for numerous applications, such as impact absorption, acoustic cloaking, photonic band gaps, and mechanical logic gates. This p…
Droplet Breakup Against an Isolated Obstacle
David J. Meer, Shivnag Sista, Mark D. Shattuck +2
We describe combined experiments and simulations of droplet breakup during flow-driven interactions with a circular obstacle in a quasi-two-dimensional microfluidic chamber. Due to…
Assessment of scoring functions for computational models of protein-protein interfaces
Jacob Sumner, Grace Meng, Naomi Brandt +4
A goal of computational studies of protein-protein interfaces (PPIs) is to predict the binding site between two monomers that form a heterodimer. The simplest version of this probl…
Cell Shape Emerges from Motion
Gautham Gopinath, Emmanuel Y. Mintah, Aashrith Saraswathibhatla +6
We perform cell segmentation on images from experimental studies of confluent, mobile cells in epithelial monolayers and show that these systems possess a broad, positively-skewed…
SCUDDO: An unsupervised clustering algorithm for single-cell Hi-C maps using diagonal diffusion operators
Luka Maisuradze, Corey S. O'Hern, Mark D. Shattuck
Motivation: Advances in high-throughput chromatin conformation capture have provided insight into the three-dimensional structure and organization of chromatin. While bulk Hi-C exp…