54 citations · 73 across the 4 of their papers we have counts for
4 papers
A novel inverse algorithm to solve IPO-IMPT of proton FLASH therapy with sparse filters
Nathan Harrison, Minglei Kang, Ruirui Liu +9
Purpose:The recently proposed IPO-IMPT framework allows simultaneous optimization of dose, dose rate, and LET for FLASH treatment planning. Finding solutions to IPO-IMPT is difficu…
Validation of the Quantum Physics Processes Underlying the Integrated Optimization of Proton FLASH Radiotherapy
Nathan Harrison, Serdar Charyyev, Cristina Oancea +6
FLASH is a new treatment modality that requires optimization of dose, dose rate, and LET. Here we validate these three quantities under FLASH conditions, which includes the quantum…
Measurement of the time structure of FLASH beams using prompt gamma rays and secondary neutrons as surrogates
Serdar Charyyev, Ruirui Liu, Xiaofeng Yang +5
We aim to investigate the feasibility of online monitoring of irradiation time (IRT) and scan time for FLASH radiotherapy using a pixelated semiconductor detector. Measurements of…
An Integrated Biological Optimization framework for proton SBRT FLASH treatment planning allows dose, dose rate, and LET optimization using patient-specific ridge filters
Ruirui Liu, Serdar Charyyev, Niklas Wahl +10
Purpose: Patient-specific ridge filters can modulate proton energy to obtain a conformal dose. We describe a new framework for optimization of filter design and spot maps to meet t…