activity
20092022
most citedFast Online Deconvolution of Calcium Imaging Data

647 citations · 1.7k across the 29 of their papers we have counts for

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Showing q-bio.NCShow all

9 papers · 1 filter

q-bio.NC2020

Chronic, cortex-wide imaging of specific cell populations during behavior

Joao Couto, Simon Musall, Xiaonan R Sun +8

Measurements of neuronal activity across brain areas are important for understanding the neural correlates of cognitive and motor processes like attention, decision-making, and act…

q-bio.NC2020★ 14 cited

A zero-inflated gamma model for deconvolved calcium imaging traces

Xue-Xin Wei, Ding Zhou, Andres Grosmark +6

Calcium imaging is a critical tool for measuring the activity of large neural populations. Much effort has been devoted to developing "pre-processing" tools for calcium video data,…

q-bio.NC2018★ 5 cited

Penalized matrix decomposition for denoising, compression, and improved demixing of functional imaging data

E. Kelly Buchanan, Ian Kinsella, Ding Zhou +17

Calcium imaging has revolutionized systems neuroscience, providing the ability to image large neural populations with single-cell resolution. The resulting datasets are quite large…

q-bio.NC2016★ 18 cited

Automated scalable segmentation of neurons from multispectral images

Uygar Sümbül, Douglas Roussien, Fei Chen +5

Reconstruction of neuroanatomy is a fundamental problem in neuroscience. Stochastic expression of colors in individual cells is a promising tool, although its use in the nervous sy…

q-bio.NC2016★ 647 cited

Fast Online Deconvolution of Calcium Imaging Data

Johannes Friedrich, Pengcheng Zhou, Liam Paninski

Fluorescent calcium indicators are a popular means for observing the spiking activity of large neuronal populations, but extracting the activity of each neuron from raw fluorescenc…

q-bio.NC2016★ 41 cited

Linear dynamical neural population models through nonlinear embeddings

Yuanjun Gao, Evan Archer, Liam Paninski +1

A body of recent work in modeling neural activity focuses on recovering low-dimensional latent features that capture the statistical structure of large-scale neural populations. Mo…

q-bio.NC2014★ 47 cited

A structured matrix factorization framework for large scale calcium imaging data analysis

Eftychios A. Pnevmatikakis, Yuanjun Gao, Daniel Soudry +6

We present a structured matrix factorization approach to analyzing calcium imaging recordings of large neuronal ensembles. Our goal is to simultaneously identify the locations of t…

q-bio.NC2013★ 12 cited

Bayesian spike inference from calcium imaging data

Eftychios A. Pnevmatikakis, Josh Merel, Ari Pakman +1

We present efficient Bayesian methods for extracting neuronal spiking information from calcium imaging data. The goal of our methods is to sample from the posterior distribution of…

q-bio.NC2013★ 18 cited

A shotgun sampling solution for the common input problem in neural connectivity inference

Daniel Soudry, Suraj Keshri, Patrick Stinson +3

Inferring connectivity in neuronal networks remains a key challenge in statistical neuroscience. The `common input' problem presents the major roadblock: it is difficult to reliabl…