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Mid-infrared Chemical Imaging of Intracellular Tau Fibrils using Fluorescence-guided Computational Photothermal Microscopy
Jian Zhao, Lulu Jiang, Alex Matlock +6
Amyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracell…
Bond-Selective Full-Field Optical Coherence Tomography
Haonan Zong, Celalettin Yurdakul, Jian Zhao +4
Optical coherence tomography (OCT) is a label-free, non-invasive 3D imaging tool widely used in both biological research and clinical diagnosis. Current OCT modalities can only vis…
Bond-Selective Intensity Diffraction Tomography
Jian Zhao, Alex Matlock, Hongbo Zhu +10
Recovering molecular information remains a grand challenge in the widely used holographic and computational imaging technologies. To address this challenge, we developed a computat…