3 papers
math.CO2026
Making ends meet or just meeting at the ends? Assessing end-to-end distance in folded RNA sequences and other branched structures
Torin Greenwood, Christine Heitsch
Researchers have repeatedly found that the ends of an RNA sequence are significantly closer than expected for a random linear chain. However, we prove that the ends of a branched s…
q-bio.BM2025
An Efficient Algorithm for Exploring RNA Branching Conformations under the Nearest-Neighbor Thermodynamic Model
Svetlana PoznanoviÄ, Owen Cardwell, Christine Heitsch
Background: In the Nearest-Neighbor Thermodynamic Model, a standard approach for RNA secondary structure prediction, the energy of the multiloops is modeled using a linear entropic…
q-bio.BM2025
Can geometric combinatorics improve RNA branching predictions?
Svetlana PoznanoviÄ, Owen Cardwell, Christine Heitsch
Prior results for tRNA and 5S rRNA demonstrated that secondary structure prediction accuracy can be significantly improved by modifying the parameters in the multibranch loop entro…