4 papers
ToFiE, a Topology-aware Fiber Extraction workflow for 3D reconstruction of dense and heterogeneous biological fiber networks from microscopy images
Risa Togo, Sara Cardona, Irène Nagle +3
Fibrous networks are ubiquitous structural components in biology, spanning cellulose in plant cell walls, fibrin in blood clots, and collagen in the extracellular matrix of animal…
Collagen and myocyte interplay in cardiac volume overload: a multi-constituent growth and remodeling framework
Ludovica Maga, Mathias Peirlinck, Lise Noël
Hearts subjected to volume overload (VO) are prone to detrimental anatomical and functional changes in response to elevated mechanical loading, ultimately leading to heart failure.…
The mechanics of the artificial heart: modeling fabric-based soft robotic devices
Marin Lauber, Maziar Arfaee, Mathias Peirlinck
Recently, the Less In More Out device, a fluidically actuated soft total artificial heart was proposed. This device uses arrays of pouch motors to achieve a positive fluidic lever…
TopoGEN: topology-driven microstructure generation for in silico modeling of fiber network mechanics
Sara Cardona, Mathias Peirlinck, Behrooz Fereidoonnezhad
The fields of mechanobiology and biomechanics are expanding our understanding of the complex behavior of soft biological tissues across multiple scales. Given the intricate connect…