3 papers
q-bio.BM2026
ConforNets: Latents-Based Conformational Control in OpenFold3
Minji Lee, Colin Kalicki, Minkyu Jeon +3
Models from the AlphaFold (AF) family reliably predict one dominant conformation for most well-ordered proteins but struggle to capture biologically relevant alternate states. Seve…
cs.CV2026
CryoHype: Reconstructing a thousand cryo-EM structures with transformer-based hypernetworks
Jeffrey Gu, Minkyu Jeon, Ambri Ma +2
Cryo-electron microscopy (cryo-EM) is an indispensable technique for determining the 3D structures of dynamic biomolecular complexes. While typically applied to image a single mole…
cs.CV2025
CryoBench: Diverse and challenging datasets for the heterogeneity problem in cryo-EM
Minkyu Jeon, Rishwanth Raghu, Miro Astore +6
Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to capture structural va…