most citedIn silico Identification of tipifarnib-like compounds by structure-based pharmacophore, virtual screening and molecular docking against K-Ras post-translation in colorectal cancer

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q-bio.BM2023★ 1 cited

In silico Identification of tipifarnib-like compounds by structure-based pharmacophore, virtual screening and molecular docking against K-Ras post-translation in colorectal cancer

Mohammed Mouhcine, Youness Kadil1, Imane Rahmoune +1

Colorectal cancer is a public health problem.Approximately 30 to 50 \% of colorectal tumors are caused by mutations in the KRAS gene.These mutations induce uncontrolled proliferati…