activity
20172023
most citedGENIUS-MAWII: For Robust Mendelian Randomization with Many Weak Invalid Instruments

7 citations · 10 across the 6 of their papers we have counts for

collaborators

6 papers

stat.ME2023

High-dimensional Feature Screening for Nonlinear Associations With Survival Outcome Using Restricted Mean Survival Time

Yaxian Chen, KF Lam, Zhonghua Liu

Feature screening is an important tool in analyzing ultrahigh-dimensional data, particularly in the field of Omics and oncology studies. However, most attention has been focused on…

stat.ME2021★ 1 cited

Semiparametric Efficient G-estimation with Invalid Instrumental Variables

Baoluo Sun, Zhonghua Liu, Eric Tchetgen Tchetgen

The instrumental variable method is widely used in the health and social sciences for identification and estimation of causal effects in the presence of potentially unmeasured conf…

stat.ME2021★ 7 cited

GENIUS-MAWII: For Robust Mendelian Randomization with Many Weak Invalid Instruments

Ting Ye, Zhonghua Liu, Baoluo Sun +1

Mendelian randomization (MR) has become a popular approach to study causal effects by using genetic variants as instrumental variables. We propose a new MR method, GENIUS-MAWII, wh…

stat.AP2021

An Eigenvalue Ratio Approach to Inferring Population Structure from Whole Genome Sequencing Data

Yuyang Xu, Zhonghua Liu, Jianfeng Yao

Inference of population structure from genetic data plays an important role in population and medical genetics studies. With the advancement and decreasing cost of sequencing techn…

stat.ME2021

A Two-Sample Robust Bayesian Mendelian Randomization Method Accounting for Linkage Disequilibrium and Idiosyncratic Pleiotropy with Applications to the COVID-19 Outcome

Anqi Wang, Zhonghua Liu

Mendelian randomization (MR) is a statistical method exploiting genetic variants as instrumental variables to estimate the causal effect of modifiable risk factors on an outcome of…

stat.AP2017★ 2 cited

A Geometric Perspective on the Power of Principal Component Association Tests in Multiple Phenotype Studies

Zhonghua Liu, Xihong Lin

Joint analysis of multiple phenotypes can increase statistical power in genetic association studies. Principal component analysis, as a popular dimension reduction method, especial…