5 citations · 6 across the 3 of their papers we have counts for
3 papers
A Causal Inference Framework for Leveraging External Controls in Hybrid Trials
Michael Valancius, Herb Pang, Jiawen Zhu +3
We consider the challenges associated with causal inference in settings where data from a randomized trial is augmented with control data from an external source to improve efficie…
Case Weighted Adaptive Power Priors for Hybrid Control Analyses with Time-to-Event Data
Evan Kwiatkowski, Jiawen Zhu, Xiao Li +3
We develop a method for hybrid analyses that uses external controls to augment internal control arms in randomized controlled trials (RCT) where the degree of borrowing is determin…
Evaluating hybrid controls methodology in early-phase oncology trials: a simulation study based on the MORPHEUS-UC trial
Guanbo Wang, Melanie Poulin Costello, Herbert Pang +6
Phase Ib/II oncology trials, despite their small sample sizes, aim to provide information for optimal internal company decision-making concerning novel drug development. Hybrid con…