6 papers
A multimodal and temporal foundation model for virtual patient representations at healthcare system scale
Andrew Zhang, Tong Ding, Sophia J. Wagner +8
Modern medicine generates vast multimodal data across siloed systems, yet no existing model integrates the full breadth and temporal depth of the clinical record into a unified pat…
Towards Spatial Transcriptomics-driven Pathology Foundation Models
Konstantin Hemker, Andrew H. Song, Cristina Almagro-Pérez +6
Spatial transcriptomics (ST) provides spatially resolved measurements of gene expression, enabling characterization of the molecular landscape of human tissue beyond histological a…
A Foundation Model for Spatial Proteomics
Muhammad Shaban, Yuzhou Chang, Huaying Qiu +57
Foundation models have begun to transform image analysis by acting as pretrained generalist backbones that can be adapted to many tasks even when post-training data are limited, ye…
Molecular-driven Foundation Model for Oncologic Pathology
Anurag Vaidya, Andrew Zhang, Guillaume Jaume +15
Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognosti…
Multimodal Whole Slide Foundation Model for Pathology
Tong Ding, Sophia J. Wagner, Andrew H. Song +20
The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transfe…
HEST-1k: A Dataset for Spatial Transcriptomics and Histology Image Analysis
Guillaume Jaume, Paul Doucet, Andrew H. Song +8
Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-increasing resolution and sensitivity. However, costs, rapidly evolving technology, and…