4 papers
Biomedical systems biology workflow orchestration and execution with PoSyMed
Simon Süwer, Zoe Chervontseva, Kester Bagemihl +3
The rapid growth of scientific software has created practical barriers for bioinformatics research. Although powerful statistical, artificial intelligence (AI)-based methods are no…
Conversational No-code, Multi-agentic Disease Module Identification and Drug Repurposing Prediction with ChatDRex
Simon Süwer, Kester Bagemihl, Sylvie Baier +5
Repurposing approved drugs offers a time-efficient and cost-effective alternative to traditional drug development. However, in silico prediction of repurposing candidates is challe…
UnPaSt: unsupervised patient stratification by biclustering of omics data
Michael Hartung, Andreas Maier, Yuliya Burankova +25
Unsupervised patient stratification is essential for disease subtype discovery, yet, despite growing evidence of molecular heterogeneity of non-oncological diseases, popular method…
A Privacy-Preserving Ecosystem for Developing Machine Learning Algorithms Using Patient Data: Insights from the TUM.ai Makeathon
Simon Süwer, Mai Khanh Mai, Christoph Klein +4
The integration of clinical data offers significant potential for the development of personalized medicine. However, its use is severely restricted by the General Data Protection R…