Opportunistic Bone-Loss Screening from Routine Knee Radiographs Using a Multi-Task Deep Learning Framework with Sensitivity-Constrained Threshold Optimization

Zhaochen Li, Xinghao Yan, Runni Zhou +8

Background: Osteoporosis and osteopenia are often undiagnosed until fragility fractures occur. Dual-energy X-ray absorptiometry (DXA) is the reference standard for bone mineral den…