2 papers
q-bio.QM2024
Timing consistency of T cell receptor activation in a stochastic model combining kinetic segregation and proofreading
Thorsten Prüstel, Martin Meier-Schellersheim
T cell receptor signaling must operate reliably under tight time constraints. While assuming quite different mechanisms, two prominent models of T cell receptor activation, kinetic…
q-bio.QM2015
Interplay of receptor memory and ligand rebinding
Thorsten Prüstel, Martin Meier-Schellersheim
Rapid rebinding of molecular interaction partners that are in close proximity after dissociation leads to a dissociation and association kinetics that can profoundly differ from pr…