4 papers
Scalable Agentic Reasoning for Designing Biologics Targeting Intrinsically Disordered Proteins
Matthew Sinclair, Moeen Meigooni, Archit Vasan +14
Intrinsically disordered proteins (IDPs) represent crucial therapeutic targets due to their significant role in disease -- approximately 80\% of cancer-related proteins contain lon…
Topology-Aware Knowledge Propagation in Decentralized Learning
Mansi Sakarvadia, Nathaniel Hudson, Tian Li +2
Decentralized learning enables collaborative training of models across naturally distributed data without centralized coordination or maintenance of a global model. Instead, device…
Workflows Community Summit 2024: Future Trends and Challenges in Scientific Workflows
Rafael Ferreira da Silva, Deborah Bard, Kyle Chard +108
The Workflows Community Summit gathered 111 participants from 18 countries to discuss emerging trends and challenges in scientific workflows, focusing on six key areas: time-sensit…
Automated, Reliable, and Efficient Continental-Scale Replication of 7.3 Petabytes of Climate Simulation Data: A Case Study
Lukasz Lacinski, Lee Liming, Steven Turoscy +7
We report on our experiences replicating 7.3 petabytes (PB) of Earth System Grid Federation (ESGF) climate simulation data from Lawrence Livermore National Laboratory (LLNL) in Cal…