2 papers
q-bio.QM2026
Scalable Agentic Reasoning for Designing Biologics Targeting Intrinsically Disordered Proteins
Matthew Sinclair, Moeen Meigooni, Archit Vasan +14
Intrinsically disordered proteins (IDPs) represent crucial therapeutic targets due to their significant role in disease -- approximately 80\% of cancer-related proteins contain lon…
q-bio.QM2025
Binding Affinity Prediction: From Conventional to Machine Learning-Based Approaches
Xuefeng Liu, Songhao Jiang, Xiaotian Duan +14
Protein-ligand binding is the process by which a small molecule (drug or inhibitor) attaches to a target protein. Binding affinity, which characterizes the strength of biomolecular…