4 papers
Effect of the dose distribution and organ architecture on the toxicity in FLASH radiotherapy: a modeling study
Juan Pardo-Montero
Objective: This study aims to investigate the influence of organ architecture (specifically the distinction between serial and parallel tissue) on the protective FLASH effect when…
Charge collection efficiency of thimble ionization chambers exposed to ultra-high dose per pulse
José Paz-MartÃn, Andreas Schüller, Marvin Apel +3
Background: Commercially available ionization chambers (ICs) exposed to ultra-high dose per pulse (UHDP) exhibit deviations from a linear dose response due to volume recombination.…
On the calculation of the radiobiological effect of radiolytic oxygen depletion in FLASH radiotherapy
Juan Pardo-Montero, Isabel González-Crespo
Objective: Radiolytic oxygen depletion (ROD) may play a role in the sparing of cells irradiated with ultra-high dose rates. Different methods have been used to quantify the effect…
Analysis of the sensitivity of tumor control probability in molecular radiotherapy to uncertainties in the dose rate curves
Pedro Otero-Casal, Aldán Baliño, Sara Neira +2
In this work, we have investigated the sensitivity of the effectiveness (TCP) of molecular radiotherapy (MRT) treatment to uncertainties of the dose rate curves that may appear whe…