8 papers
minAction.net: Energy-First Neural Architecture Design -- From Biological Principles to Systematic Validation
Martin G. Frasch
Modern machine learning optimizes for accuracy without explicit treatment of internal computational cost, even though physical and biological systems operate under intrinsic energy…
Inter-Electrode Pulse Wave Velocity: A Direct Method for Maternal Arterial Stiffness Assessment During Pregnancy Using Multi-Channel ECG
Nicolas B. Garnier, Marlene J. E. Mayer, Clara Becker +3
Objective: To validate a novel inter-electrode pulse wave velocity (PWV) method that measures pulse propagation between ECG electrodes without left ventricular ejection time (LVET)…
Prenatal Stress Detection from Electrocardiography Using Self-Supervised Deep Learning: Development and External Validation
Martin G. Frasch, Marlene J. E. Mayer, Clara Becker +4
Prenatal psychological stress affects 15-25% of pregnancies and increases risks of preterm birth, low birth weight, and adverse neurodevelopmental outcomes. Current screening relie…
Minimum-Action Learning: Energy-Constrained Symbolic Model Selection for Physical Law Identification from Noisy Data
Martin G. Frasch
Identifying physical laws from noisy observational data is a central challenge in scientific machine learning. We present Minimum-Action Learning (MAL), a framework that selects sy…
Dose-Dependent Cardiac Complexity Changes in Children Following Prenatal Glucocorticoid Exposure: Complementary Evidence from Multiscale Entropy Analysis and ECG Foundation Models
Nicolas B. Garnier, Michelle Dreiling, Valeska Kozik +3
\noindent\textbf{Background} Prenatal glucocorticoid exposure alters cardiac development, but whether persistent cardiac effects in childhood follow a dose-response relationship re…
Measuring the time-scale-dependent information flow between maternal and fetal heartbeats during the third trimester
Nicolas B. Garnier, Maria S. Molinet, Marta C. Antonelli +2
Prenatal maternal stress alters maternal-fetal heart rate coupling, as demonstrated by the Fetal Stress Index derived from bivariate phase-rectified signal averaging. Here, we exte…