Time to revisit the endpoint dilution assay and to replace TCID${}_{50}$ and PFU as measures of a virus sample's infection concentration

Daniel Cresta, Donald C. Warren, Christian Quirouette +4

The infectivity of a virus sample is measured by the infections it causes, via a plaque or focus forming assay (PFU or FFU) or an endpoint dilution (ED) assay (TCID${}_{50}$, CCID$_{…