2 papers
q-bio.QM2023
Modeling Path Importance for Effective Alzheimer's Disease Drug Repurposing
Shunian Xiang, Patrick J. Lawrence, Bo Peng +4
Recently, drug repurposing has emerged as an effective and resource-efficient paradigm for AD drug discovery. Among various methods for drug repurposing, network-based methods have…
cs.LG2023
Enhancing drug and cell line representations via contrastive learning for improved anti-cancer drug prioritization
Patrick J. Lawrence, Xia Ning
Due to cancer's complex nature and variable response to therapy, precision oncology informed by omics sequence analysis has become the current standard of care. However, the amount…