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physics.flu-dyn2023
In vitro evaluation of solution-based pressurised metered dose inhaler sprays with low GWP propellants
Daniel Duke, Lingzhe Rao, Benjamin Myatt +4
BACKGROUND: The impending transition from high Global Warming Potential (GWP) propellants such as HFA134a to low-GWP alternatives such as HFA152a and HFO1234ze(E) in pressurised me…
physics.flu-dyn2023★ 6 cited
Canister valve and actuator deposition in metered dose inhalers formulated with low-GWP propellants
Daniel J Duke, Lingzhe Rao, Alan Kastengren +6
A challenge in pressurised metered-dose inhaler formulation design is management of adhesion of the drug to the canister wall, valve and actuator internal components and surfaces,…