1 citations · 1 across the 3 of their papers we have counts for
4 papers
Benchmarking virtual cell models for in-the-wild perturbation response
Xinjie Mao, Songming Zhang, Qianhong Wen +10
Virtual cell (VC) models aim to predict cellular responses to any perturbations in silico and have emerged as a promising approach for drug discovery and precision medicine. Yet, a…
AblateCell: A Reproduce-then-Ablate Agent for Virtual Cell Repositories
Xue Xia, Chengkai Yao, Mingyu Tsoi +10
Systematic ablations are essential to attribute performance gains in AI Virtual Cells, yet they are rarely performed because biological repositories are under-standardized and tigh…
HarmonyCell: Automating Single-Cell Perturbation Modeling under Semantic and Distribution Shifts
Wenxuan Huang, Mingyu Tsoi, Yanhao Huang +10
Single-cell perturbation studies face dual heterogeneity bottlenecks: (i) semantic heterogeneity--identical biological concepts encoded under incompatible metadata schemas across d…
Accurate de novo sequencing of the modified proteome with OmniNovo
Yuhan Chen, Shang Qu, Zhiqiang Gao +13
Post-translational modifications (PTMs) serve as a dynamic chemical language regulating protein function, yet current proteomic methods remain blind to a vast portion of the modifi…