most citedApplying the estimands framework to non-inferiority trials: guidance on choice of hypothetical estimands for non-adherence and comparison of estimation methods

1 citations · 1 across the 1 of their papers we have counts for

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stat.ME2023★ 1 cited

Applying the estimands framework to non-inferiority trials: guidance on choice of hypothetical estimands for non-adherence and comparison of estimation methods

Katy E Morgan, Ian R White, Clémence Leyrat +2

A common concern in non-inferiority (NI) trials is that non adherence due, for example, to poor study conduct can make treatment arms artificially similar. Because intention to tre…