collaborators

1 paper

stat.ME2023

Applying the estimands framework to non-inferiority trials: guidance on choice of hypothetical estimands for non-adherence and comparison of estimation methods

Katy E Morgan, Ian R White, Clémence Leyrat +2

A common concern in non-inferiority (NI) trials is that non adherence due, for example, to poor study conduct can make treatment arms artificially similar. Because intention to tre…