most citedPreparing to Integrate Generative Pretrained Transformer Series 4 models into Genetic Variant Assessment Workflows: Assessing Performance, Drift, and Nondeterminism Characteristics Relative to Classifying Functional Evidence in Literature

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q-bio.GN2023★ 1 cited

Preparing to Integrate Generative Pretrained Transformer Series 4 models into Genetic Variant Assessment Workflows: Assessing Performance, Drift, and Nondeterminism Characteristics Relative to Classifying Functional Evidence in Literature

Samuel J. Aronson, Kalotina Machini, Jiyeon Shin +8

Background. Large Language Models (LLMs) hold promise for improving genetic variant literature review in clinical testing. We assessed Generative Pretrained Transformer 4's (GPT-4)…