30 citations · 31 across the 4 of their papers we have counts for
4 papers
Efficiency of Multivariate Tests in Trials in Progressive Supranuclear Palsy
Elham Yousefi, Mohamed Gewily, Franz König +6
Measuring disease progression in clinical trials for testing novel treatments for multifaceted diseases as Progressive Supranuclear Palsy (PSP), remains challenging. In this study…
Simultaneous inference procedures for the comparison of multiple characteristics of two survival functions
Robin Ristl, Heiko Götte, Armin Schüler +2
Survival time is the primary endpoint of many randomized controlled trials, and a treatment effect is typically quantified by the hazard ratio under the assumption of proportional…
Methods for non-proportional hazards in clinical trials: A systematic review
Maximilian Bardo, Cynthia Huber, Norbert Benda +13
For the analysis of time-to-event data, frequently used methods such as the log-rank test or the Cox proportional hazards model are based on the proportional hazards assumption, wh…
Optimizing Trial Designs for Targeted Therapies
Thomas Ondra, Sebastian Jobjörnsson, Robert A. Beckman +4
An important objective in the development of targeted therapies is to identify the populations where the treatment under consideration has positive benefit risk balance. We conside…