2 papers
q-bio.QM2023
Inferring the dynamics of ionic currents from recursive piecewise data assimilation of approximate neuron models
Stephen A. Wells, Joseph D. Taylor, Paul G. Morris +1
We construct neuron models from data by transferring information from an observed time series to the state variables and parameters of Hodgkin-Huxley models. When the learning peri…
q-bio.QM2023
Single shot diagnosis of ion channel dysfunction from assimilation of cell membrane dynamics
Paul G Morris, Joseph D. Taylor, Julian F. R. Paton +1
Many neurological diseases originate in the dysfunction of cellular ion channels. Their diagnosis presents a challenge especially when alterations in the complement of ion channels…