602 citations · 1k across the 4 of their papers we have counts for
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Design principles of transcription factors with intrinsically disordered regions
Wencheng Ji, Ori Hachmo, Naama Barkai +1
Transcription Factors (TFs) are proteins crucial for regulating gene expression. Effective regulation requires the TFs to rapidly bind to their correct target, enabling the cell to…
Asymptotic Cellular Growth Rate as the Effective Information Utilization Rate
Rami Pugatch, Naama Barkai, Tsvi Tlusty
We study the average asymptotic growth rate of cells in randomly fluctuating environments, with multiple viable phenotypes per environment. We show that any information processing…
The Iterative Signature Algorithm for the analysis of large scale gene expression data
Sven Bergmann, Jan Ihmels, Naama Barkai
We present a new approach for the analysis of genome-wide expression data. Our method is designed to overcome the limitations of traditional techniques, when applied to large-scale…
Mechanisms of noise-resistance in genetic oscillators
Jose M. G. Vilar, Hao Yuan Kueh, Naama Barkai +1
A wide range of organisms use circadian clocks to keep internal sense of daily time and regulate their behavior accordingly. Most of these clocks use intracellular genetic networks…