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stat.ME2026
Testing Procedures for Strict Pleiotropy in Genetic Association Studies
Eva Biswas, Nilanjan Chatterjee, Zheyu Wang
Pleiotropy, the phenomenon in which a single genetic variant influences multiple traits, is a fundamental feature of genome biology and an important consideration in statistical ge…
stat.ME2024
Constructing Genetic Risk Scores: Robust Bayesian Approach through Projected Summary Statistics and Flexible Shrinkage
Yuzheng Dun, Nilanjan Chatterjee, Jin Jin +1
Polygenic risk scores (PRS) developed from genome-wide association studies (GWAS) can be used for risk stratification by quantifying the genetic contribution to disease, and many c…