8 citations · 8 across the 2 of their papers we have counts for
2 papers
q-bio.SC2024
Target search in the CRISPR/Cas9 system: Facilitated diffusion with target cues
Qiao Lu, Simone Pigolotti
We study how Cas9, a central component of the CRISPR/Cas9 system, searches for a target sequence on the DNA. We propose a model that includes as key ingredients 3D diffusion, 1D sl…
q-bio.SC2021★ 8 cited
Search and localization dynamics of the CRISPR/Cas9 system
Qiao Lu, Deepak Bhat, Darya Stepanenko +1
The CRISPR/Cas9 system acts as the prokaryotic immune system and has important applications in gene editing. The protein Cas9 is one of its crucial components. The role of Cas9 is…