232 citations · 236 across the 4 of their papers we have counts for
4 papers
Implications of self-identified race, ethnicity, and genetic ancestry on genetic association studies in biobanks within health systems
Ruth Johnson, Bogdan Pasaniuc
Precision medicine aims to create biomedical solutions tailored to specific factors that affect disease risk and treatment responses within the population. The success of the genom…
Generalizability of PRS313 for breast cancer risk amongst non-Europeans in a Los Angeles biobank
Helen Shang, Yi Ding, Vidhya Venkateswaran +5
Polygenic risk scores (PRS) summarize the combined effect of common risk variants and are associated with breast cancer risk in patients without identifiable monogenic risk factors…
A Bayesian method for estimating gene-level polygenicity under the framework of transcriptome-wide association study
Arunabha Majumdar, Bogdan Pasaniuc
Polygnicity refers to the phenomenon that multiple genetic variants have a non-zero effect on a complex trait. It is defined as the proportion of genetic variants that have a nonze…
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
Bogdan Pasaniuc, Noah Zaitlen, Huwenbo Shi +7
Imputation using external reference panels is a widely used approach for increasing power in GWAS and meta-analysis. Existing HMM-based imputation approaches require individual-lev…