3 papers
physics.bio-ph2024
Factors influencing the stability of the motor-clutch model on compliant substrates under external load
Beibei Shen, Yunxin Zhang
Cellular migration is crucial for biological processes including embryonic development, immune response, and wound healing. The myosin-clutch model is a framework that describes ho…
physics.bio-ph2023
Cooperation of myosin II in muscle contraction through nonlinear elasticity
Beibei Shen, Yunxin Zhang
Myosin II plays a pivotal role in muscle contraction by generating force through the cooperative action of multiple motors on actin filaments. In this study, we integrate the nonli…
physics.bio-ph2021
Biochemical pathways of forward/backward steps of motor protein kinesin-1
Beibei Shen, Yunxin Zhang
Kinesin-1 is an ATP-driven, two-headed motor protein that transports intracellular cargoes along microtubule. Based on recent experimental observations, we formulate a mechanochemi…